Frank Lampard knocked old boss Jose Mourinho out of the EFL Cup as Derby County beat Manchester United on penalties, while Burton Albion triumphed against Burnley.
Marouane Fellaini's late equaliser took Tuesday's tie to a shootout following a 2-2 draw at Old Trafford, with Scott Carson saving Phil Jones' poor penalty to complete a dramatic 8-7 success for the Championship side.
Harry Wilson and Jack Marriott had earlier struck for the Rams as Lampard enjoyed a memorable reunion with Mourinho, his manager at Chelsea.
United's rivals Manchester City made short work of League One side Oxford United as the holders progressed to the fourth round thanks to a 3-0 win.
Phil Foden helped to create goals for Gabriel Jesus and Riyad Mahrez before scoring his first goal for the club to wrap up a star performance.
Yeeeeeeessss @PhilFoden— Fernandinho (@fernandinho) September 25, 2018
Along with United's exit, the other big shock of the day came at Burton, where Burnley's awful cup competitions record under Sean Dyche continued with a 2-1 loss.
Kevin Long's header gave the Premier League team the lead, but League One Burton hit back through Liam Boyce, who then set up Jamie Allen for a late winner.
Penalties were needed in the all-Premier League tie at Molineux, with Danny Ward saving three spot-kicks after a goalless draw to book Leicester City a fourth-round berth at the expense of Wolves.
Go on the Warden Penalty saving masterclass @dan_ward52— James Maddison (@Madders10) September 25, 2018
Callum Wilson scored a 94th-minute winner to secure a 3-2 home victory for Bournemouth against Blackburn Rovers, while Andros Townsend struck twice as Crystal Palace won 3-0 at West Brom.
Jordan Rhodes' hat-trick booked Norwich City's progression with a 4-3 thriller at Wycombe Wanderers, with 15-year-old Harvey Elliott making his Fulham debut in their 3-1 win at Millwall.
Middlesbrough scored all four of their penalties to edge through in a shootout after drawing 2-2 with Preston North End, while Blackpool are in the last 16 after a 2-0 home win against 10-man QPR.
19 de febrero 2019
|Solskjaer hails ´massive´ result against Chelsea after PSG loss|
|Two-time Open 13 champion Simon avoids upset against Hoang|
|Sarri worried by results, not fans´ jeers|
|Mickelson, Tiger learn WGC-Mexico Championship groupings|
18 de febrero 2019
|Serena aiming to surpass Court´s major record this year - Mouratoglou|
|Solskjaer trusts us, we trust him – Pogba|
|Vettel revels in ´unbelievable´ start to F1 testing, Williams woe continues|
|Man United visit Wolves in FA Cup last eight, Swansea to host Man City|
|Giants manager Bruce Bochy to retire after 2019 season|
|Nurnberg 0 Borussia Dortmund 0: Stalemate leaves Bayern within striking distance|
|Chelsea 0 Manchester United 2: Solskjaer´s men bounce back to reach FA Cup quarter-finals|
|Wozniacki explains ongoing struggle with viral illness after Dubai withdrawal|
|Petkovic drops just one game against Bogdan in Budapest|
|Barcelona have learned from Roma humiliation - Valverde|
|Djokovic and Biles take top Laureus honours|
|Leeds United fined £200,000 by EFL following spying controversy|
|Tiger Woods wins Laureus World Comeback of the Year Award|
|Gundogan marvels at Man City team-mate David Silva|
|Djokovic can match Nadal and Federer in major honours - Becker|
|Ribery doubtful for Liverpool trip after daughter´s birth|
|Webb outlines commitment to Toulon after president´s outburst|
|Griezmann: Champions League home final gives us extra motivation|
|Salihamidzic and Bayern not daunted by ´special´ Anfield atmosphere|
|Serena returns to WTA top 10 for first time as a mother|
|Saunders to fight Isufi for vacant WBO super-middleweight belt|
|West Ham reveal plans to improve London Stadium atmosphere|
|Wasps sign Minozzi and announce it with ´Super Mario´ mash-up|
|Unwell Wozniacki pulls out of Dubai Tennis Championship|
|Dananjaya returns to Sri Lanka squad for South Africa ODIs|
|Henderson targets Premier League and Champions League double|
|Hogg ruled out as Townsend adds six to Scotland squad|
|Cancellara backs Cavendish to claim more stage wins|
|Tyson Fury agrees lucrative deal to be co-promoted by Top Rank|
|Leeds United suffer blow with Roofe injury|
|Klopp fears Bayern Munich are ´more dangerous than before´|
|Rosberg: Hamilton favourite again and pressure on Vettel|
|Klopp assessing Lovren ´minute by minute´ ahead of Bayern|
|Paratici confirms Juventus enquiry over Icardi|
|I am still contracted to my team - Savea responds to Toulon owner´s bizarre outburst|
|Carter sad for retiring Lambie but excited to make Racing return|
|Harvey to step down as EFL CEO|
|IAAF calls on five experts as Semenya challenges hyperandrogenism rule via CAS|
|Shaqiri has silenced doubters at Liverpool, says Barnetta|
|I´ll try to keep racking them up - Durant wants more after All-Star MVP|
|Coman back but no Boateng for Bayern Munich´s trip to Liverpool|
|Kaepernick may not want to return to the NFL - Allen|
|Foden dwelling on one mistake over decisive Newport double|
|LeBron focusing on Lakers´ playoff push after All-Star Game|
|Liverpool are favourites against Bayern Munich - Kimmich|
|Squire leaving New Zealand to join Red Hurricanes|
|Liverpool v Bayern Munich: James desperately needs a career boost at Anfield|
|Clash with ultras, stripped of captaincy - a timeline of Icardi´s fractured Inter relationship|
|Ospina will remain at Napoli next season, says Ancelotti|
|Antetokounmpo shines, Nowitzki and Wade can still play – takeaways from NBA All-Star Game|
|Top highlights from Team LeBron´s victory over Team Giannis in NBA All-Star Game|
|Durant earns All-Star Game MVP honours|
|Team LeBron rally past Team Giannis|
|PSG can reach Champions League final without Neymar – Cafu|
|Holmes edges out Thomas to win fifth PGA Tour event|
|Hamlin wins crash-filled Daytona 500|
|Marotta: Inter have never doubted Icardi|
|Guardiola was questioned too – Zola says Sarri needs time|
|Icardi has no intention to leave Inter - Nara|
|Tuchel hails ´exceptional´ PSG mentality|
|Mbappe: PSG team better than my goals record|
|Opelka claims maiden ATP title in New York|
|Mbappe makes Ligue 1 history with wonderful volley|
|Saudi takeover of Manchester United dismissed|
17 de febrero 2019
|Stroman unhappy with Blue Jays´ lack of veteran leadership|
|Sanchez is far from finished at the top level, insists Solskjaer|