Frank de Boer's Atlanta United suffered another defeat as their stuttering MLS title defence continued, while Nani's late winner saw Orlando City past Vancouver Whitecaps.
Lowly Atlanta were upstaged by FC Dallas 2-1 on Saturday – leaving De Boer's side without a victory at home in the league this season.
Atlanta attempted 22 shots at Mercedes-Benz Stadium, where Jesus Ferreira and Bryan Acosta silenced the hosts.
Josef Martinez converted a penalty deep into stoppage-time but it was merely a consolation for Atlanta, who have only won three games in all competitions since former Inter and Crystal Palace boss De Boer replaced Gerardo Martino.
Plenty of chances to build on.— Atlanta United FC (@ATLUTD) April 21, 2019
Highlights from today's match pic.twitter.com/yWSk2Rsea5
Atlanta are second from bottom in the Eastern Conference with five points from six matches, while Dallas are fourth in the west.
Ex-Manchester United winger and Portuguese star Nani led Orlando to a 1-0 win against the visiting Whitecaps.
Nani deflected Sacha Kljestan's 88th-minute shot beyond Vancouver goalkeeper Zac MacMath for his fourth MLS goal since arriving from Sporting CP.
Former Atletico Madrid midfielder Nicolas Gaitan set up two goals in Chicago Fire's 4-1 rout of winless Colorado Rapids, who ended the match with 10 men.
After Colorado's Kei Kamara cancelled out Nemanja Nikolic's opener prior to half-time, the Fire scored three unanswered goals following the break via Charles Sapong, Djordje Mihailovic and Aleksandar Katai.
Rapids midfielder Jack Price was sent off with four minutes remaining in Chicago to compound Colorado's misery.
Elsewhere, New England edged New York Red Bulls 1-0, Portland Timbers ended their winless start to the season by defeating Columbus Crew 3-1, Philadelphia Union accounted for Montreal Impact 3-0 and San Jose Earthquakes crushed Sporting Kansas City 4-1.
26 de mayo 2019
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|Liverpool want to emulate Man City dominance – Henderson|
|Marcelino revels in ´happiest day´ after Copa del Rey success|
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|Na leads at Colonial, Spieth two shots back|
|Valverde vows to fight on at Barcelona|
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25 de mayo 2019
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|Toulon end Castres´ reign, La Rochelle and Montpellier seal play-off spots|
|Coutinho, Semedo & Arthur start Copa del Rey final after injury problems|
|Yastremska shrugs off Garcia to claim maiden clay title|
|Gasly handed Monaco grid penalty|
|Without him, I would have one title – Hamilton dedicates Monaco pole to Lauda|
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|Carapaz takes Maglia Rosa after climbing to stage 14 win|
|Injured Keita named in Guinea´s provisional AFCON squad|
|Wiesberger leads at Made in Denmark after Schwab struggles|
|Edouard brace fires Celtic to historic treble-treble|
|Paire picks off Auger Aliassime in Lyon final|
|Leclerc demands Ferrari answers and prays for rain after Monaco farce|
|Putintseva claims first WTA title at Nuremberg Cup|
|Gattuso: Champions League not imperative for Milan job prospects|
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